TRIBROMOMETHYL PHENYL SULFONE (PHENYL TRIBROMOMETHYL SULFONE)

TRIBROMOMETHYL PHENYL SULFONE
PRODUCT IDENTIFICATION
CAS NO.	17025-47-7
EINECS NO.	241-096-6
FORMULA	C₆H₅SO₂CBr₃
MOL WT.	392.89
H.S. CODE	2904.90.4000
TOXICITY
SYNONYMS	Tribromo Methyl Sulphonyl Benzene; Tribromomethyl phenyl sulfone;
Phenyl tribromomethyl sulfone; [(tribromomethyl)sulfonyl]-Benzene;
SMILES	O=S(=O)(c1ccccc1)C(Br)(Br)Br
CLASSIFICATION	photosensitive material
EXTRA NOTES
PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE	white crystalline powder
MELTING POINT	145 - 149 C
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER
AUTOIGNITION
pH
VAPOR DENSITY
NFPA RATINGS
REFRACTIVE INDEX
FLASH POINT
STABILITY	Stable under ordinary conditions
EXTERNAL LINKS & GENERAL DESCRIPTION
Wikipedia Linking - Photoinitiator Google Scholar Search PubChem Compound Summary - Tribromomethyl phenyl sulfone http://www.ebi.ac.uk/chebi/ - Tribromomethyl phenyl sulfone http://www.ncbi.nlm.nih.gov/ - Tribromomethyl phenyl sulfone Material Safety Data Sheet http://www.beilstein-journals.org/ A halogenmethylsulfonyl moiety is incorporated in numerous active herbicides and fungicides. The synthesis of tribromomethyl phenyl sulfone derivatives as novel potential pesticides is reported. The title sulfone was obtained by following three different synthetic routes, starting from 4-chlorothiophenol or 4-halogenphenyl methyl sulfone. Products of its subsequent nitration were subjected to the S_NAr reactions with ammonia, amines, hydrazines and phenolates to give 2-nitroaniline, 2-nitrophenylhydrazine and diphenyl ether derivatives. Reduction of the nitro group of 4-tribromomethylsulfonyl-2-nitroaniline yielded the corresponding o-phenylenediamine substrate for preparation of structurally varied benzimidazoles. Local: Polymerization is initiated generally by free radical. There are four types of free radical initiators which initiate polymerization. Peroxides including hydroperoxides (tertiary-butyl hydroperoxide, benzoylperoxide) Azocompound thermal initiators (azoisobutyronitrile) Redoxinitiators (mixture of iron(III) acetylacetonate): free radicals are formed by one-electron transferreactions. Useful in low temperature and emulsion polymerization Photoinitiators (benzoin, benzil dimethylketal) The main advantage of polymerization started by photoinitiators is temperature-independence and easy control. It can be conducted at very low temperatures and can be stopped simply by removing the light source. Photoinitiators are compounds that break down into free radicals upon exposure to ultraviolet radiation. Photoinitiators undergo a unimolecular bond cleavage upon irradiation to yield free radicals (benzoin esters; benzil ketals; alpha-dialkoxy acetophenones; alpha-hydroxy-alkylphenones; alpha-amino alkyl- phosphine; acylphosphine oxides). Another type of photoinitiators undergo a bimolecular reaction where the excited state of the photoinitiator interacts with a second molecule (a coinitiator) to generate free radicals(benzo phenones,amines; thioxanthones,amines; titanocenes). Photoinitiators are widely applied in UV curing inks, wood coatings, paper coatings, optical fiber, PCB, screen printing , paper varnish and other surface coatings. The common examples of sulfone compounds are dapsone (4,4'-sulfonylbisbenzenamine) and its derivative. Dapsone (4,4'-sulfonylbisbenzenamine) is a parent compound in preparing sulfonamide antibacterial agents such as acedapsone, acetosulfone, glucosulfone, sulfoxone and solapsone. Dapsone and its derivatives have bacteriostatic activity against a broad spectrum of gram-negative and gram-positive organisms. Dapsone is a primary treatment for Dermatitis herpetiformis and in the treatment of leprosy (Mycobacterium leprae infections) leads to apparent improvementas. It is used in the prophylaxis of falciparum malaria. It is a white crystalline powder; melting point 175 - 180C; insoluble in water and vegetable oils. Dapsone is also widely used in polymer industry as a cross linkage agent in manufacturing polysulfone amide engineering plastics. Sulfone-containing engineering plastics are thermally stable and have high resistance property to acids and alkalis. Tazobactam is a penicillanic acid sulfone derivative which acts as a beta-lactamase inhibitor similar to sulbactam. Tazobactam is used in combination with piperacillin to widen the spectrum of activity. Sulfone class compounds which have a sulfonyl group attached to two carbon atoms are active as an antibiotic. Tribromomethyl phenyl sulfone is used as a photoinitiator for UV-curable systems, inks and varnishes. It is used as an intermediate for the synthesis of pharmaceuticals and other organic compounds.
SALES SPECIFICATION
APPEARANCE	white crystalline powder
ASSAY	99.0% min
MELTING POINT	143 - 147 C
BROMINE CONTENT	ca 60%
ASH	0.1% max
LOSS ON DRYING	0.5% max
TRANSPORTATION
PACKING
HAZARD CLASS
UN NO.
SAFETY INFORMATION
HAZARD OVERVIEW
GHS
SIGNAL WORD	Warning
PICTOGRAMS
HAZARD STATEMENTS	H319 Causes serious eye irritation H317 May cause an allergic skin reaction
PRECAUTIONARY STATEMENTS	P310 Immediately call a POISON CENTER or doctor/physician P280 Wear eye protection/face protection P501 Dispose of contents/container through a waste management company authorized by the local government.
EC DIRECTIVES
HAZARD CODES	Xi Irritant
RISK PHRASES	36/37/38: Irritating to eyes, respiratory system and skin
SAFETY PHRASES	26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 37/39 Wear suitable gloves and eye/face protection
PRICE INFORMATION